From: julie
To: againstslaughter@yahoogroups.com
Sent: Thursday, February 26, 2004 7:02 PM
Subject: [againstslaughter] Vetipulmin/Clenbuterol

I have been on the internet all day looking at the different medications that horse receive.  Almost all of the medications clearly state that they are not to be used on horses intended for food. A good website to get information on the different medications is. http://www.farad.org/ Food Animal Residue Avoidance Databank Homepage.  Also use the keyword (Clenbuterol in horses) and you will get a lot of information. When doing this research
Vetipulmin/Clenbuterol stood out more than the others. Here is some of the information on what I found.
Julie
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Clenbuterol was illegally used in show animals..(1995)
http://www.fsis.usda.gov/OA/background/clenbute.htm
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Clenbuterol becomes legal in 1998
http://www.fda.gov/cvm/index/updates/clenbut.htm
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****This states that USE IN FOOD-ANIMALS PROHIBITED*****


Vetipulmin ® Syrup      Rx      140-973

Manufactured by :      Boehringer Ingelheim Vetmedica, Inc.
      Presently Marketed

Therapeutic Drug
Formulation:      Each ml of sterile aqueous solution contains 72.5 mcg
of clenbuterol hydrochloride.     

Warnings:      The effect of this drug on breeding stallions and
brood mares has not been determined. Treatment starting with dosages
higher than the initial dose is not recommended.

Route:      - Oral
      Dosage Form:      - Solution

Active Ingredients(s):      - Clenbuterol hydrochloride
      Drug Classification(s):      - Respiratory Agents, Other
      - USE IN FOOD-ANIMALS PROHIBITED


Horses

Meat Withdrawal:      N/V 
      Additional W/D Time:      N/V
      Milk Withdrawal:       N/V 


Indications:      Use for the management of horses affected with airway
obstruction, such as occurs in chronic obstructive pulmonary disease
(COPD).

Directions:      Administer orally twice a day (b.i.d.). Initial dose
is 0.5 ml/100 lb bwt (0.8 mcg/kg) for 3 days (6 treatments). If no
improvement, administer 1 ml/100 lb (1.6 mcg/kg) for 3 days (6
treatments). If no improvement, administer 1.5 ml/100 lb (2.4 mcg/kg)
for 3 days (6 treatments). If no improvement, administer 2.0 ml/100
lb (3.2 mcg/kg) for 3 days (6 treatments). If no improvement, horse
is nonresponder to clenbuterol and treatment should be discontinued.
Treat at effective dose for 30 days. At the end of the 30-day
treatment period, drug should be withdrawn. If signs return, the 30-
day treatment period may be repeated. If repeating treatment, the
step-wise dosage schedule should be repeated.

Further Information:      The effect of this drug on breeding stallions
and brood mares has not been determined. Treatment starting with
dosages higher than the initial dose is not recommended. Federal law
prohibits the extralabel use of this drug in food animals.


References:
CFR:      520.452
Fed. Reg.      08/04/98 (41419)
Last Federal Register Update      8/4/98
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*This statement was made before Clenbuterol became legal.*

STATEMENT BY
DAVID A. KESSLER, M.D.,COMMISSIONER OF FOOD AND DRUGS. DEPARTMENT OF
HEALTH AND HUMAN SERVICES. BEFORE THE SUBCOMMITTEE ON
AGRICULTURE,RURAL DEVELOPMENT, AND RELATED AGENCIES COMMITTEE ON
APPROPRIATIONS UNITED STATES SENATE MAY 2, 1996


Another important consumer protection action, carried out in
cooperation with the U.S. Customs Service and the U.S. Department of
Agriculture, halted the smuggling into the U.S. of large quantities
of clenbuterol and other unapproved drugs that were then mixed in
feed sold to veal producers throughout the Midwest. Clenbuterol is
used in some countries to increase muscle in animals, but traces of
the drug in meat products have caused outbreaks of food poisoning in
France and Spain. FDA discovered that the drug was reaching this
country when it appeared in animals shown in agricultural
competitions. The indicted Wisconsin feed distributor is awaiting
sentencing
http://www.fda.gov/ola/1996/kessler2.html
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